Cedarburg Hauser Pharmaceuticals

CASE STUDY:
New Process Development for the Flavor Industry


Cedarburg Hauser Pharmaceuticals was contracted to develop a process for a key intermediate in the flavor industry with the criteria that the process eliminate a complex chromatography, be scalable to metric tons, and reduce 100-fold the cost per kilogram.

Cedarburg was able to significantly improve a literature procedure which replaced elemental sulfur chemistry with a mercaptan variant and substantially improved the process. We eliminated chromatography, significantly reduced processing time, simplified purification, removed lingering odor and coloration issues, met the original price objectives and provided material of greater than 99% assay in good yields, thereby meeting or exceeding all of the original project goals.