Case Studies

Cedarburg Hauser has a proven track record developing and manufacturing complex APIs. We have successfully worked with our clients on a variety of projects including API conjugates, prostaglandins, natural products and pharmaceutical intermediates. .  

The conifdental nature of our business prevents us from disclosing all of the details of these projects, however, share the type of work we did and the overall achievements help give a sense of our track record of success. Please take a moment to review these case histories and then contact us to discuss your project. 

Development and GMP Manufacture of a Polymeric Conjugate Including a Potent, Controlled Substance
Cedarburg Hauser successfully developed, optimized, scaled and manufactured a potent, controlled substance polymeric conjugate API.  Working closely with our client we were able to meet their aggressive timeline and generate 1.3 kg of the target API conjugate under GMP conditions for their clinical trials.  The material was high purity and the final optimized process produced an overall yield of 52%.   More details…

Development and GMP Manufacture of a Peptide Conjugate Including a Potent Therapeutic Agent
Cedarburg Hauser successfully produced a peptide conjugate API under GMP conditions at 25 times the scale ever achieved prior to our involvement.  We were able to provide enough high purity material for our client’s phase II clinical trial needs.  We were also able to develop and generate high purity material of a second conjugate to satisfy their needs for their toxicology studies, phase I clinical trials and reference standards.  More details…

Development and GMP Manufacture of a Anti-Cancer Peptide Conjugate
Through careful study, Cedarburg Hauser scientists were able to identify and optimize key chromatographic parameters that resulted in an improved separation, a significantly increased resin life, and an overall process yield increase to 65-70%.   The conjugate API was delivered on schedule and exceeded the customer requested amount by >10%..  More details…

Process Transfer and Optimization for an Anti-Cancer Agent

New Process Development for the Flavor Industry

New Process Development for a Commercial Prostaglandin

Enhancement and Isolation Process Development of a Natural Product