Natural Product Extraction, Isolation and Purification

Cedarburg Hauser Pharmaceuticals is a world leader in the extraction, isolation, purification and synthetic modification of natural products from plant, marine and microbial sources. We produce ingredients for pharmaceuticals, personal care products, and dietary supplements.

Services

* Research scale studies
* Bioassay guided fractionation
* Isolation and identification of actives
* Standards isolation and characterization
* Process development
* Process scale-up and optimization
* Semi-synthetic natural product modification
* Custom manufacturing
* Chemical analysis
* Consultancy
* Taxane standards sale

All work is supported by a highly sophisticated analytical laboratory noted for its high quality and innovative work.

Capabilities

Cedarburg Hauser Pharmaceutical's state-of-the-art facilities include small-scale bench top laboratories, pilot-scale laboratories and commercial manufacturing suites equipped to perform:

* Extraction
* Ultra filtration
* Synthesis
* Precipitation
* Chromatographic separation
* Distillation
* Crystallization
* Solids drying
* Filtration
* Lyophilization

We specialize in the purification of high value and high potency chemicals from complex mixtures. We have developed proprietary extraction and purification technology, Dynamic Liquid / Solid Extraction (DLSESM) and Liquid / Liquid Focusing (LLFSM).

More traditional types of chromatography - including Prep-HPLC and large scale, medium and low pressure chromatography along with automated fractionation - are used to purify a variety of materials from natural sources.

Cedarburg Hauser Pharmaceuticals has a proven track record in assisting clients in the development of natural products with innovative and cost effective processes.

Some examples of products are:

* Paclitaxel from Yew biomass (pharmaceutical cGMP), taxanes
* Michellamine B (pharmaceutical cGMP)
* Artemisinin
* Tea catechins (pharmaceutical cGMP)
* Natural fatty acids, sterols, terpenes, isoflavones, polysaccharides, alkaloids, nucleosides, and saponins
* Personal care ingredients (anti-oxidants)
* Plant proteins